Induction of tumor necrosis factor alpha by spherules of Coccidioides immitis
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چکیده
منابع مشابه
Serological comparison of spherules and arthrospores of Coccidioides immitis.
Spherule and arthrospore cellular preparations were sonic-treated and separated into their respective supernatant and sediment components. Complement-fixation tests with antispherule and antiarthrospore pooled rabbit sera revealed that the soluble antigens exhibited more serological activity than the sediment preparations. After autoclaving, an arthrospore cellular antigen exhibited increased a...
متن کاملElectron Microscopy of Cultured Spherules of Coccidioides Immitis
Spherules of C. immitis have been grown in vitro in modified Roessler's medium under CO(2) tension and continuous cultures now maintained for over 18 months. Transformation of hyphae and development of the spherule form have been studied by thin section electron microscopy. Cells of organisms in the hyphal stage have thin (ca. 50 mmicro), apparently structureless walls and a cytoplasmic membran...
متن کاملContinuous in Vitro Cultivation of Spherules of Coccidioides Immitis.
Breslau, Abraham M. (Veterans Administration Center and University of California Los Angeles Center for the Health Sciences, Los Angeles, Calif.), and Mike Y. Kubota. Continuous in vitro cultivation of spherules of Coccidioides immitis. J. Bacteriol. 87:468-472. 1964.-Spherules of Coccidioides immitis were grown in vitro in continuous culture for more than 4 years. Cultures were grown in modifi...
متن کاملEvaluation of Tumor Necrosis Factor Alpha Polymorphism Frequencies in Endometriosis
Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are important factors in reproductive-related disorders. One of the most common gynecological diseases of women during the reproductive years is endo...
متن کاملEffects of lysozyme and chitinase on the spherules of Coccidioides immitis in vitro.
Spherules of Coccidioides immitis strain Silveira produced in vitro were treated with chitinase and lysozyme. The walls of merthiolate-killed mature endosporulating spherules were degraded by chitinase (500 mug/ml) and by lysozyme (100 and 500 mug/ml). Thus, as was visible through the light microscope, the spherule wall was reduced in thickness from 1 to 2 mum to less than 0.5 mum. The degradat...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1989
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.57.7.1916-1921.1989